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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0508 | γ-Aminobutyric acid | Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid | GABA Receptor , Endogenous Metabolite |
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system. | |||
T38225 | N-Arachidonoyl-3-hydroxy-γ-Aminobutyric Acid | ||
Several different arachidonoyl amino acids, including N-arachidonoyl-3-hydroxy-γ-aminobutyric acid (NAG-3H-ABA), have been isolated and characterized from bovine brain. The glycine congener was further characterized and ... | |||
TN1023 | Miltirone | P450 , GABA Receptor | |
Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors. | |||
T2990 | Phenibut | Phenybut,Fenigam,Fenibut,PhGABA,Aminophenylbutyric acid,β-Phenyl-γ-aminobutyric acid | GABA Receptor |
Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA). | |||
T4440 | Saclofen | GABA Receptor | |
Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).1 This compound can be used to determine the function... | |||
TQ0023 | Lorediplon | GABA Receptor | |
Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep. | |||
T5754 | Kavain | NF-κB , GABA Receptor | |
Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors such as NF-kB and LITAF. | |||
T14571 | Bifenazate | GABA Receptor | |
Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm. | |||
TQ0119 | Cirsimaritin | GABA Receptor | |
Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors. | |||
T15775 | Lotilaner | GABA Receptor , Parasite | |
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor. | |||
T10618 | Broflanilide | GABA Receptor | |
Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL GABAR (IC50: 1.3 nM). | |||
T7794 | Zuranolone | GABA Receptor | |
Zuranolone is an agonist of GABAA receptor. | |||
T7557 | Guvacine hydrochloride | GABA Receptor | |
Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM) | |||
T3782 | Jujuboside A | transporter , GABA Receptor | |
Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, having neurophysiological inhibitory effects, used as a potential therapeutic agent for the treatment of Alzheimer s disease. | |||
T1065 | Baclofen | Lioresal | GABA Receptor |
Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp... | |||
T8036 | 6-Methylflavone | GABA Receptor | |
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. | |||
T16539 | Piperazine citrate | GABA Receptor | |
Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmintic. | |||
T5375 | Loreclezole | GABA Receptor | |
Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors. | |||
T26600 | Alpidem | Ananxyl | GABA Receptor |
Alpidem (Ananxyl) is an anxiolytic drug from the imidazopyridine family. Alpidem does not produce sedative effects at normal doses, and is instead used specifically for the treatment of anxiety. Alpidem has nanomolar bin... | |||
T3644 | U93631 | GABA Receptor | |
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GABA-induced Cl- currents with little effect on peak amplitude... |